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Initiating dextromethorphan-bupropion extended release in patients with major depressive disorder: Delphi panel expert consensus recommendations
Clayton, A. H., Alva, G., Bowman, P., Crown, E., Das, B., Doghramji, P., … Miller, J. J. (2026). Initiating dextromethorphan-bupropion extended release in patients with major depressive disorder: Delphi panel expert consensus recommendations. Current Medical Research and Opinion, 42(6), 1243–1256. https://doi.org/10.1080/03007995.2026.2700073 Abstract…
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Vagus Nerve Stimulation in Difficult-to-Treat Depression: When Does It Work Best?
Author(s)Gustavo Alva, MD, DFAPA Where can vagus nerve stimulation fit into treating depression? View video on YouTube Gus Alva, MD, discussed vagus nerve stimulation (VNS) as an underutilized but clinically important neuromodulation option in the stepwise management of difficult-to-treat depression, from the…
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COMP360 Psilocybin in Treatment-Resistant Depression: Insights From Gus Alva, MD, DFAPA
Author(s)Gustavo Alva, MD, DFAPA Phase 3 COMP360 psilocybin data show lasting TRD relief; experts explain brain-network reset, therapy support, and what approval could mean. View video on YouTube Gus Alva, MD, discussed the current state of psychedelic research in psychiatry, with particular…
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Starting ADHD Treatment in Adolescents, With Ann Childress, MD
Author(s)Gustavo Alva, MD, DFAPA, Ann Childress, MD Expert shares ADHD medication sequencing tips and practical insomnia strategies, from stimulants to melatonin, for kids and adults. View video on YouTube Ann Childress, MD, discussed clinical approaches to medication sequencing in attention-deficit hyperactivity disorder…
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Breaking Barriers in Schizophrenia: Optimizing Adherence, Outcomes, and Collaborative Care
In this Psychiatric Times Peer Exchange, the panel delves into a comprehensive examination of schizophrenia care, covering the clinical and economic burden of the disease, the multifactorial challenges of treatment adherence, and the evolving landscape of pharmacological options — from first-generation antipsychotics…
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9 Spravato (Esketamine) Side Effects & How to Deal With Them
Key Takeaways Every Spravato dose is given at a certified clinic, and staff watch you for at least two hours afterward. Most side effects show up within minutes of your dose and fade well before you leave. Side effect How common Typical…
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Neuropsychological Testing: What It Is & How It Works
Key Takeaways Neuropsychological Testing Explained Neuropsychological testing gives your doctor a detailed picture of how your brain handles everyday demands. A standard office visit might check your reflexes or ask a few screening questions. The evaluation measures specific areas through hands-on activities.…
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Borderline Personality Disorder (BPD) vs. Bipolar Disorder
Key Takeaways BPD vs. Bipolar Disorder: Key Differences BPD (borderline personality disorder is a personality disorder, while bipolar disorder is a mood disorder. That single distinction shapes everything about how each condition behaves and how it’s treated. A mood disorder involves depression…
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Schizophrenia vs. Schizoaffective Disorder: Key Differences & Treatments
Key Takeaways Mental health diagnoses can feel like a maze, especially when conditions share similar traits. If you or someone you love has noticed symptoms that blur the lines between reality and inner chaos, you know how hard it can be to…
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Can Adults Suddenly Develop ADHD? Symptoms Checklist
Many adults who suddenly find themselves struggling with focus, organization, and emotional regulation ask the same question: “Did I just catch ADHD?” The short answer is complex, but medically, the consensus is no.You cannot “catch” ADHD in your 30s or 40s like…
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How to Get Your Life Together When Overwhelmed
You know the feeling: the laundry pile has become a permanent fixture, your inbox is a source of physical pain, and you cannot remember the last time you felt truly rested. This is not just “having a bad week.” It is a…
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7 Proven Bipolar Disorder Treatments That Work
Bipolar disorder is a mental health condition characterized by extreme mood swings that include emotional highs (mania or hypomania) and lows (depression). Treatment is absolutely essential because it provides the tools and medical support needed to manage these shifts, reduce the severity…
Mental health
resources & insights
Expert guidance on psychiatric conditions, treatments, and mental wellness written and reviewed by PNS providers.