-
Initiating dextromethorphan-bupropion extended release in patients with major depressive disorder: Delphi panel expert consensus recommendations
Clayton, A. H., Alva, G., Bowman, P., Crown, E., Das, B., Doghramji, P., … Miller, J. J. (2026). Initiating dextromethorphan-bupropion extended release in patients with major depressive disorder: Delphi panel expert consensus recommendations. Current Medical Research and Opinion, 42(6), 1243–1256. https://doi.org/10.1080/03007995.2026.2700073 Abstract Objective To establish consensus recommendations for initiating dextromethorphan–bupropion extended release (45 mg/105 mg) (AUVELITY) for…
-
Vagus Nerve Stimulation in Difficult-to-Treat Depression: When Does It Work Best?
Author(s)Gustavo Alva, MD, DFAPA Where can vagus nerve stimulation fit into treating depression? View video on YouTube Gus Alva, MD, discussed vagus nerve stimulation (VNS) as an underutilized but clinically important neuromodulation option in the stepwise management of difficult-to-treat depression, from the 2026 Southern California Psychiatry conference. Alva described the current landscape of interventional options…
-
COMP360 Psilocybin in Treatment-Resistant Depression: Insights From Gus Alva, MD, DFAPA
Author(s)Gustavo Alva, MD, DFAPA Phase 3 COMP360 psilocybin data show lasting TRD relief; experts explain brain-network reset, therapy support, and what approval could mean. View video on YouTube Gus Alva, MD, discussed the current state of psychedelic research in psychiatry, with particular focus on the clinical trial program for COMP360 psilocybin by Compass Pathways in…
-
Starting ADHD Treatment in Adolescents, With Ann Childress, MD
Author(s)Gustavo Alva, MD, DFAPA, Ann Childress, MD Expert shares ADHD medication sequencing tips and practical insomnia strategies, from stimulants to melatonin, for kids and adults. View video on YouTube Ann Childress, MD, discussed clinical approaches to medication sequencing in attention-deficit hyperactivity disorder (ADHD) and management of comorbid insomnia in pediatric and adult patients with ADHD,…
-
Breaking Barriers in Schizophrenia: Optimizing Adherence, Outcomes, and Collaborative Care
In this Psychiatric Times Peer Exchange, the panel delves into a comprehensive examination of schizophrenia care, covering the clinical and economic burden of the disease, the multifactorial challenges of treatment adherence, and the evolving landscape of pharmacological options — from first-generation antipsychotics to novel mechanisms of action and alternative delivery systems. The series emphasizes the…
